Research Scientist (iPSC)

We are also at the forefront of innovation with our iPSC-derived CAR-macrophages, offering a groundbreaking approach in solid tumors treatment. In addition, we are developing next-generation exosome and oncolytic virus therapeutic products to overcome the lack of effective treatment options for cancer and chronic diseases.

We are seeking to recruit a Research Scientist to work in the research and development field of cell and gene therapy new drug development. This is an excellent mid-to-high level job for candidates interested in pursuing industry experience/or developing skillsets in cellular and molecular analysis with pluripotent stem cell background.

Job Requirements:

1. Design and draft the experiment plan independently. Execute the experiment plan with the team, troubleshooting, data collection and analysis, and draft the experiment report. Ensure all experiments and results are recorded completely and systematically.
2. Design and perform experiments including but not limited to cell culture, especially induced pluripotent stem cell (iPSC) culture, cell line creation, characterization and cell engineering, stem cell reprogramming and differentiation, flow cytometry, ELISA, qPCR, immunofluorescence, molecular design and cloning, and other cell-based experiments.
3. Responsible for the process development research for scaling up the iPSC culture in defined conditions. Develop research plans and proposals for the process development, and carry out related research work.
4. Responsible for the development of biological analytical methods for iPS cells and their derivatives and writing of report documents.
5. Responsible for the technology transfer related to cell culture and upstream process.
6. Ensure that standard operating procedures and safety regulations are followed.
7. Assist in supervising, training and guiding new colleagues or team members when required.
8. Read, analyse and interpret scientific literature and patents, and summarize the new technologies for translational research.
9. Author or review protocols, experiment records, technical reports, and technology transfer documents. Author research manuscript and technology disclosure per required.

Qualifications:

1. A PhD degree or a Master’s degree with 3 years of working experience in Cell Biology, Molecular Biology or in any related field with pluripotent stem cells.
2. Extensive experience in iPSC culture, generation and differentiation is required.
3. Strong background and working experience in basic molecular and cellular biological techniques are preferred, including molecular cloning, cell culture, stable cell line creation and engineering, Western Blot, real-time PCR, ELISA, FACS, etc.
4. Strong background or understanding in immunology, immunoregulation, and transcriptome analysis is preferred.
5. Prior experience in cell line genetic modification, gene editing such as CRISPR, small RNAs, nanoparticle and exosome characterization is a plus.
6. Familiar with the product design and process optimization will be given priority.
7. Creative, capable of independent thinking, and strong self-learning ability.
8. Strong sense of responsibility, self-disciplined, hardworking, resilient, with entrepreneurial passion, willing to grow with the company.
9. Good communication skills and teamwork spirit.

Location: Singapore

Apply now by submitting a CV to hr@neocytogen.com

We regret that only shortlisted candidates will be contacted.